导师姓名：刘北东
性别：
人气指数：48

所属院校：浙江农林大学
所属院系：
职称：教授
导师类型：博导
招生专业：风景园林学
研究领域： 利用酵母高通量筛选平台从事细胞抗逆性及衰老机理的研究
研究领域： 利用酵母高通量筛选平台从事细胞抗逆性及衰老机理的研究 [收起]




个人简述 :
刘北东，博士，以酵母为研究对象建立了大规模表型组研究系统，主要从事细胞衰老以及胁迫条件下的细胞信号通路和调节机制等方面的研究。独立主持瑞典国家自然科学基金、瑞典癌症研究基金等多项基金项目。并在高水平学术期刊发表论文20余篇（平均影响因子11.75），其中以第一作者在Cell杂志上发表论文2篇，共同作者发表1篇，以通讯作者在Science杂志上发表论文1篇。

科研工作 :
主要论文:1. Beidong Liu*, Lisa Larsson, Antonio Caballero, Xinxin Hao, David Oling, Julie Grantham, and Thomas Nystrom* (2010). The polarisome is required for segregation and retrograde transport of protein aggregates. Cell 140, 257-267.2. Beidong Liu*, Lisa Larsson, Vanessa Franssens, Xinxin Hao, Sandra M. Hill, Veronica Andersson, Daniel Hoglund, Jia Song, Xiaoxue Yang, David Oling, Julie Grantham, Joris Winderickx, and Thomas Nystrom* (2011). Segregation of protein aggregates involves actin and the polarity machinery. Cell 147, 959-961.3. Sandra Malmgren Hill, Xinxin Hao, Beidong Liu*, and Thomas Nystr?m* (2014). Life-span extension by a metacaspase in the yeast Saccharomyces cerevisiae. Science 344, 1389-1392.4. Jia Song, Qian Yang, Junsheng Yang, Lisa Larsson, Xinxin Hao, Xuefeng Zhu, Sandra Malmgren-Hill, Marija Cvijovic, Julia Fernandez-Rodriguez, Julie Grantham, Claes M. Gustafsson, Beidong Liu*, and Thomas Nystr?m (2014). Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates. PLOS Genetics 10, e**.5. Xiaoxue Yang, Yi Shen, Elena Garre, Xinxin Hao, Daniel Krumlinde, Marija Cvijovi?, Christina Arens, Thomas Nystr?m, Beidong Liu*, and Per Sunnerhagen* (2014). Stress Granule-Defective Mutants Deregulate Stress Responsive Transcripts. PLOS Genetics 10, e**.6. Junsheng Yang, Xinxin Hao, Xiuling Cao, Beidong Liu*, and Thomas Nystr?m* (2016). Spatial sequestration and detoxification of Huntingtin by the ribosome quality control complex. eLife 5, e11792.7. Sandra M. Hill, Xinxin Hao, Johan Gronvall, Stephanie Spikings-Nordby, Per O. Widlund, Triana Amen, Anna Jorhov, Rebecca Josefson, Daniel Kaganovich, Beidong Liu*, and Thomas Nystrom* (2016). Asymmetric Inheritance of Aggregated Proteins and Age Reset in Yeast Are Regulated by Vac17-Dependent Vacuolar Functions. Cell Rep 16, 826-838.8. Sarah Hanzen, Katarina Vielfort, Junsheng Yang, Friederike Roger, Veronica Andersson, Sara Zamarbide-Fores, Rebecca Andersson, Lisa Malm, Gael Palais, Benoit Biteau, Beidong Liu, Michel B. Toledano, Mikael Molin* and Thomas Nystrom* (2016). Lifespan Control by Redox-Dependent Recruitment of Chaperones to Misfolded Proteins. Cell 166, 140-151.