导师姓名：苏志坚
性别：男
人气指数：54

所属院校：暨南大学
所属院系：生命科学技术学院
职称：研究员
导师类型：硕导
招生专业：
研究领域： 生殖生物学，基因工程药物，生物工程
研究领域： 生殖生物学，基因工程药物，生物工程 [收起]




通讯方式 :
办公电话：**
电子邮件：tjnuszj@jnu.edu.cn


科研工作 :
（1）Yang Y, Li Z, Wu X, Chen H, Ge R, Chen J, Su Z*, Huang Y*. Direct reprogramming of mouse fibroblasts toward Leydig-like cells by defined factors. Stem Cell Reports, 2017 8(1):39-53（A1）（2）Xiao X, Zhang C, Liu D, Bai W, Zhang Q, Xiang Q, Huang Y*, Su Z*. Prevention of gastrointestinal lead poisoning using recombinant Lactococcus lactis expressing human metallothionein-I fusion protein. Sci Rep. 2016 Apr 56:23716. doi: 10.1038/srep23716. （A1）（3）Dai X, Sun Z, Liang R, Li Y, Luo H, Huang Y, Chen M, Su Z*, Xiao F*. Recombinant Nogo-66 via soluble expression with SUMO fusion in Escherichia coli inhibits neurite outgrowth in vitro. Appl Microbiol Biotechnol. 2015, 99(14):5997-6007.（A1）（4）Yang Y#, Su Z#, Xu W, Luo J, Liang R, Xiang Q, Zhang Q, Ge RS, Huang Y. Directed mouse embryonic stem cells into leydig-like cells rescue testosterone-deficient male rats in vivo. Stem Cells Dev. 2015，24(4):459-70.（A1）（5）Liu H, Yang Y, Zhang L, Liang R, Ge RS, Zhang Y, Zhang Q, Xiang Q, Huang Y*, Su Z*. Basic fibroblast growth factor promotes stem Leydig cell development and inhibits LH-stimulated androgen production by regulating microRNA expression. J Steroid Biochem Mol Biol. 2014, 144 Pt B:483-91. （A1）（6）Hu H, Xiang Q, Liu H, Qu H, Tang X, Xiao X, Zhang Q, Su Z*, Huang Y*. Expression, purification, and biological activity of the recombinant pramlintide precursor. Appl Microbiol Biotechnol. 2014, 98(18):7837-44. （A1）（7）Dai X, Cai C, Xiao F, Xiong Y, Huang Y, Zhang Q, Xiang Q, Lou G, Lian M, Su Z*, Zheng Q*. Identification of a novel aFGF-binding peptide with anti-tumor effect on breast cancer from phage display library. Biochem Biophys Res Commun. 2014, 445(4):795-801. （A2）（8）Sun J, Bai S, Bai W*, Zou F, Zhang L, Li G, Hu Y, Li M, Yan R, Su Z*, Huang Y. 1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells. Food Chem. 2014, 154:330-6. （A1）（9）Zhang L, Wang H, Yang Y, Liu H, Zhang Q, Xiang Q, Ge R, Su Z*, Huang Y*. NGF induces adult stem Leydig cells to proliferate and differentiate during Leydig cell regeneration. Biochem Biophys Res Commun. 2013, 436(2):300-5. （A2）（10）Zhang M, Qiu Z, Li Y, Yang Y, Zhang Q, Xiang Q, Su Z*, Huang Y*. Construction and characterization of a recombinant human beta defensin 2 fusion protein targeting the epidermal growth factor receptor: in vitro study. Appl Microbiol Biotechnol. 2013, 97(9):3913-23. （A1）（11）Su Z, Zhang M, Liu X, Tong L, Huang Y, Li G, Pang Y. Comparison of bacterial diversity in wheat bran and in the gut of larvae and newly emerged adult of Musca domestica (Diptera: Muscidae) by use of ethidium monoazide reveals bacterial colonization. J Econ Entomol. 2010, 103(5):1832-41. （A2）（12）Chen X, Chen Z, Chen H, Su Z, Yang J, Shi S He X. Nucleosomes suppress spontaneous mutations base-specifically in eukaryotes. Science, 2012，335 (6073): 1235-1238.（A1）

教育背景 :
2010/06－2011/09 美国洛克菲勒大学暨人口委员会，博士后；2005/09－2009/12 中山大学，生命科学学院，博士；1998/09－2001/07 中山大学，生命科学学院，硕士 ；1994/09－1998/07 中山大学，生命科学学院，学士。