导师姓名：高聪
性别：女
人气指数：54

所属院校：广州医科大学
所属院系：
职称：教授
导师类型：硕导
招生专业：神经病学


个人简述 :
高聪，女， 1958年8月出生，籍贯河北，民盟盟员，学历本科，医学学士学位，广州医科大学神经病学教研室教授，博士研究生导师，中国免疫学会神经免疫分会全国委员，广东省医学会神经病学分会免疫学组副组长。曾获得广东省“南粤优秀教师”广州市优秀教师等称号。工作业绩近十余年来，从事多发性硬化、视神经脊髓炎的临床与实验系列研究，共承担、参与了省市级多个有关多发性硬化的科研课题，在SCI、国家级核心期刊发表相关论文20多篇。近年来，AQP4抗体、纳米材料、miRNA成为研究关注的焦点，课题组在与时俱进，建立了AQP4抗体检测、纳米材料介导的基因表达和基因沉默技术平台，试图为视神经脊髓炎的诊断、分型、转归及预后判断寻找新的分子标志物，为视神经脊髓炎的生物治疗提供新的有效手段。此外，一直从事青年卒中的临床研究，在国际期刊中发表了近10篇有关于青年卒中的研究论文，为我国青年卒中的临床特点提供了重要的资料。培养条件本课题组培养研究生的重点培养内容是：基本功必须扎实、协作精神必须强、培养科学研究兴趣；研究内容一方面在理论上冲击国际前沿科学，另一方面要注意与临床相结合，重点在于诊断标志物和预后指标的研究，神经影像学的改变亦为课题组的研究方向。欢迎有志者加盟我们的团队。?

科研工作 :
近期论文（第一作者或通讯作者）
1.???????? Long Y, Zheng Y, Chen M, Zhang B, Gao C, Shan F, Yang N, Fan Y. Serum thyroid-stimulating hormone and anti-thyroglobulin antibody are independently associated with lesions in spinal cord in central nervous system demyelinating diseases.PLoS One. 2014 Aug 59(8):e**.???????? Yang N, Zhang B, Xie L, Yin J, He Y, Yang X, Gao C.The association baseline NIH Stroke Scale score with ABO blood-subtypes in young patients with acute ischemic stroke.Atherosclerosis. 2014 Jul 11236(1):144-149.3.???????? Long Y, Zheng Y, Shan F, Chen M, Fan Y, Zhang B, Gao C, Gao Q, Yang N.Development of a cell-based assay for the detection of anti-aquaporin 1 antibodies in neuromyelitis optica spectrum disorders.J Neuroimmunol. 2014 Aug 15273(1-2):103-104.???????? Zhang B, Yang N, Gao C.Is plasma C3 and C4 levels useful in young cerebral ischemic stroke patients? Associations with prognosis at 3 months.J Thromb Thrombolysis. 2014 Jun 18. [Epub ahead of print]5.???????? Long Y, Gao C.Brain embolism secondary to cardiac myxoma in fifteen Chinese patients.ScientificWorldJournal. 2014 Mar 92014:**.???????? Long Y, Zheng Y, Chen M, Zhang B, Gao C, Gao Q, Yin JR, Pu S, Xie C.Antineutrophil cytoplasmic antibodies in patients with idiopathic inflammatory-demyelinating diseases.Neuroimmunomodulation. 201421(6):297-303. 7.???????? Long Y, Chen M, Zhang B, Gao C, Zheng Y, Xie L, Gao Q, Yin J. Brain gadolinium enhancement along the ventricular and leptomeningeal regions in patients with aquaporin-4 antibodies in cerebral spinal fluid. J Neuroimmunol. 2014 Apr 15269(1-2):62-7.8.???????? long Y, He Y, Zheng Y, Chen M, Zhang B, Gao C. Serum anticardiolipin antibodies in patients with neuromyelitis optica spectrum disorder.J Neurol. 2013 Dec260(12):3150-7.9.???????? Gao C, Huang L, Long Y, Zheng J, Yang J, Pu S, Xie L.Y-39983, a selective Rho-kinase inhibitor, attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination.Neuroimmunomodulation. 201320(6):334-40. 10.???? Yang N, Zhang B, Gao C.The baseline NIHSS score in female and male patients and short-time outcome: a study in young ischemic stroke.J Thromb Thrombolysis. 2014 May37(4):565-70.11.???? Long Y, Gao C, Qiu W, Hu X, Peng F, Lu Z.Antibodies target microvessels in neuromyelitis optica and multiple sclerosis patients. Neurol Res. 2013 Nov35(9):922-9.12.???? Liang B, Deng JJ, Yuan F, Yang N, Li W, Yin JR, Pu SX, Xie LC, Gao C, Zhang LM.Efficient gene transfection in the neurotypic cells by star-shaped polymer consisting of β-cyclodextrin core and poly(amidoamine) dendron arms.Carbohydr Polym. 2013 Apr 1594(1):185-92.13.???? Zhang B, Gao C, Hou Q, Yin J, Xie L, Pu S, Yi Y, Gao Q.The potent different risk factors for cerebral infarction in young patients with and without type 2 diabetes: subanalysis of the Young Cerebral Infarction Study (YCIS).Atherosclerosis. 2012 Mar221(1):215-20. 14.???? Zhang B, Gao C, Hou Q, Yin J, Xie L, Pu S, Yi Y, Gao Q.Different independent susceptibility markers for first-ever cerebral infarction and myocardial infarction in young patients.J Neurol. 2012 Jul259(7):1420-5. 15.???? Zhang B, Zhang W, Li X, Pu S, Yin J, Yang N, Yi Y, Gao Q, Gao C.Admission markers predict lacunar and non-lacunar stroke in young patients.Thromb Res. 2011 Jul128(1):14-7. 16.???? Zhang B, Pu S, Zhang W, Yang N, Shen G, Yin J, Yi Y, Gao Q, Gao C.Sex differences in risk factors, etiology, and short-term outcome of cerebral infarction in young patients.Atherosclerosis. 2011 Jun216(2):420-5. 17.???? Zhang B, Gao C, Yang N, Zhang W, Song X, Yin J, Pu S, Yi Y, Gao Q.Is elevated SUA associated with a worse outcome in young Chinese patients with acute cerebral ischemic stroke?BMC Neurol. 2010 Sep 1810:82.18.???? Gao C, Zhang B, Zhang W, Pu S, Yin J, Gao Q.Serum prealbumin (transthyretin) predict good outcome in young patients with cerebral infarction.Clin Exp Med. 2011 Mar11(1):49-54. 19.???? Zhang B, Song X, Liang B, Hou Q, Pu S, Ying JR, Gao C.The clinical study of POEMS syndrome in China.Neuro Endocrinol Lett. 201031(2):229-37.20.???? Zhang B, Pu S, Li B, Ying J, Song XW, Gao C.Comparison of serum apolipoprotein A-I between Chinese multiple sclerosis and other related autoimmune disease.Lipids Health Dis. 2010 Mar 299:34.
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教育背景 :
学习经历:1982年毕业于中山医科大学（现中山大学），获学士学位，毕业后一直在广州医科大学附属医院工作，从事神经病学专业的临床、教学和科研工作。