导师姓名：郭艳苏
性别：女
人气指数：72

所属院校：河北医科大学
所属院系：
职称：主任医师
导师类型：
招生专业：神经病学


通讯方式 :
办公电话：**
电子邮件：gys188@163.com


个人简述 :
郭艳苏，女，河北医科大学第二医院神经内科，主任医师，教授，硕士生导师。河北省医学会神经病学分会青年委员。2013.4-2015.3美国马萨诸塞大学医学院访问学者。研究方向为神经变性疾病及神经病理。先后主持国家自然科学基金1项、河北省自然科学基金1项、河北省科技厅重点基础研究项目2项、河北省卫生厅医学科学研究重点课题6项。获河北省科技进步二等奖2项、河北省科技进步三等奖1项。发表SCI论文38篇，著作1部。培养硕士研究生6名。被评为河北医科大学中青年骨干教师，获第七届石家庄市青年科技奖。

科研工作 :
1．Guo Y, Wang D, Qiao T, Yang C, Su Q, Gao G, Xu Z. A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord. Mol Neurobiol. 201653(5):3235-48. 2. An T, Shi P, Duan W, Zhang S, Yuan P, Li Z, Wu D, Xu Z, Li C, Guo Y*. Oxidative Stress and Autophagic Alteration in Brainstem of SOD1-G93A Mouse Model of ALS. Mol Neurobiol, 2014 49(3):1435-48. 3. Zhang K, Shi P, An T, Wang Q, Wang J, Li Z, Duan W, Li C, Guo Y*. Food restriction- induced autophagy modulates degradation of mutant SOD1 in an amyotrophic lateral sclerosis mouse model. Brain Res. 2013 1519: 112-9. 4. Guo Y, Zhang Y, Wen D, Duan W, An T, Shi P, Wang J, Li Z, Chen X, Li C. The modest impact of transcription factor Nrf2 on the course of disease in an ALS animal model. Lab Invest. 2013 93(7): 825-33. 5. Guo Y, Wang Q, Zhang K, An T, Shi P, Li Z, Duan W, Li C. HO-1 induction in motor cortex and intestinal dysfunction in TDP-43 A315T transgenic mice. Brain Res. 2012 1460: 88-95. 6. Guo Y, Zhang K, Wang Q, Li Z, Yin Y, Xu Q, Duan W, Li C. Neuroprotective effects of diallyl trisulfide in SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis. Brain Res. 2011 1374: 110-5. 7. Guo Y, Duan W, Li Z, Huang J, Yin Y, Zhang K, Wang Q, Zhang Z, Li C. Decreased GLT-1 and increased SOD1 and HO-1 expression in astrocytes contribute to lumbar spinal cord vulnerability of SOD1-G93A transgenic mice. FEBS Lett. 2010 584(8): 1615-22. 8. Guo Y, Li C, Wu D, Wu S, Yang C, Liu Y, Wu H, Li Z. Ultrastructural Diversity of Inclusions and Aggregations in the Lumbar Spinal Cord of SOD1-G93A Transgenic Mice. Brain Res, 2010 1353: 234-244. 9. Guo Y, Liu Y, Xu L, Wu D, Wu H, Li CY. Reduced Nrf2 and Phase II Enzymes Expression in Immune-mediated Spinal Cord Motor Neuron Injury. Neurol Res. 2010 32(5): 460-5.