导师姓名：刘洪卓
性别：女
人气指数：99

所属院校：沈阳药科大学
所属院系：药学院
职称：副教授
导师类型：硕导
招生专业：药剂学、药学（药剂学方向）
研究领域： 研究方向一：内耳药物传递系统研究方向二：高分子纳米复合材料研究方向三：物理药学
研究领域： 研究方向一：内耳药物传递系统研究方向二：高分子纳米复合材料研究方向三：物理药学 [收起]




通讯方式 :
电子邮件：liuhongzhuo@syphu.edu.cn
通讯地址：沈阳市沈河区文化路103号23#


个人简述 :
刘洪卓，女，博士，副教授。2002年毕业于沈阳药科大学，获药学学士学位，2007年于同校获药物制剂博士学位，毕业后赴美国University of Cincinnati进行博士后研究。作为课题负责人主持了国家自然科学基金青年、面上基金项目各1项，辽宁省高等学校杰出青年学者成长计划1项，另外，作为项目骨干成员承担国家自然科学基金面上项目3项。目前已论文40余篇。

科研工作 :
近年来发表代表性论文：1.ZhenjieWang, Xiao Kuang, Jia Shi, Weiling Guo and Hongzhuo Liu*, Targeted delivery ofgeranylgeranylacetone to mitochondria by triphenylphosphonium modifiednanoparticles: a promising strategy to prevent aminoglycoside-induced hearingloss, Biomater Sci, 2017, 5(9):1800-1809.（IF 4.21）2.Xiao Kuang,Yanhui Sun, Zhenjie Wang, Shuang Zhou, Hongzhuo Liu*, A mitochondrial targetingtetrapeptide Bendavia protects lateral line hair cells from gentamicinexposure, J Appl Toxicol, 2017, DOI:10.1002/jat.3547.（IF 4.21）3.Jiang M,Zhang R, Wang Y, Jing W, Liu Y, Ma Y, Sun B, Wang M, Chen P, Liu H*, He Z. Reduction-sensitivePaclitaxel Prodrug Self-assembled Nanoparticles with Tetrandrine EffectivelyPromote Synergistic Therapy Against Drug-sensitive and Multidrug-resistantBreast Cancer, Mol Pharm, 2017, doi: 10.1021/acs.molpharmaceut.7b00381. （IF 4.44）4.Chan Jin,Jibin Guan, Dong Zhang, Bing Li, Hongzhuo Liu* and Zhonggui He*, Supercriticalfluid chromatography coupled with tandem mass spectrometry: A high-efficiencydetection technique to quantify Taxane-drugs in whole blood samples, J Sep Sci,2017, doi: 10.1002/jssc.**.（IF 2.56）5.Xin Che,Zhenjie Wang, Yining Liu, Yanhui Sun , Hongzhuo Liu*, Sustained release ofnerve growth factor from highly homogenous cubosomes stabilized by β-caseinwith enhanced bioactivity and bioavailability, RSC Advances, 2016, 6,114676-114684.（IF 3.10）6. Che Xin,Wang Lihong, Li Qiuyuan, Liu Hongzhuo*, Injectable long-term control-releasedin situ gels of hydrochloric thiothixene for the treatment of schizophrenia:Preparation, in vitro and in vivo preparation. Int J Pharm, 2014, 469(1):23-30.（IF 3.65）7.Meng Bu,Jingling Tang, Yinghui Wei, Yanhui Sun, Xinyu Wang, Linhua Wu*, Hongzhuo Liu*,Enhanced bioavailability of nerve growth factor with phytantriol lipid-based crystallinenanoparticles in cochlea, Int J Nanomedicine，2015 310:6879-89. （IF 4.32）8.Jiayu Xin,Jingling Tang, Meng Bu, Yanhui Sun, Xinyu Wang, Linhua Wu* and Hongzhuo Liu*, Anovel eye drop of alpha tocopherol to prevent ocular oxidant damage: improve thestability and ocular efficacy, Drug Dev Ind Pharm, 2016 42(4): 525–534. （IF 2.11）9.ZhenhuaHuang, Heran Li, Qian Zhang, Xiaojuan Tan, Fangzheng Lu, Hongzhuo Liu*, andSanming Li*, Characterization of preclinical in vitro and in vivopharmacokinetics properties for KBP-7018, a new tyrosine kinase inhibitorcandidate for treatment of idiopathic pulmonary fibrosis, Drug Design,Development and Therapy 2015:9 4319–4328.（IF 2.88）10.HongzhuoLiu, Michael B. Yang, S. Kevin Li and Jinsong Hao, Effects of Dosing Protocolon Distribution of Propranolol in Periocular Tissues after Topical OcularInstillation, Curr Eye Res. 2015 May40(6):638-45.（IF 2.02）