导师姓名：李娟
性别：女
人气指数：133

所属院校：中国药科大学
所属院系：药学院
职称：教授
导师类型：博导
招生专业：药剂学、药学（工业药学方向）
研究领域： *新型药用高分子材料与靶向释药系统研究*缓/控释释药系统与药代动力学研究*药物新剂型与新技... [展开]


研究领域： *新型药用高分子材料与靶向释药系统研究*缓/控释释药系统与药代动力学研究*药物新剂型与新技术研究 [收起]




通讯方式 :
办公电话：**
电子邮件：lijuancpu@163.com
通讯地址：江苏省南京市童家巷24号药学院 药剂系


个人简述 :
李娟：女，教授，博士，博士生导师，六大人才高峰高层次人才，农工民主党员，江苏省农工妇委会委员。药学院，药剂系骨干教师，曾担任药剂学实验室主任20年。教育部优秀硕博论文和新药项目评审专家，国家科技进步奖评审专家，国家重大专项和江苏省科技项目审评专家，2008作为国家新药审评专家，审评过渡期新药。为国外多家SCI杂志Journal of Pharmaceutical Sciences、International Journal of Pharmaceutics、Reactive and Functional Polymers、Advances in Polymer Technology等审稿人。为国内《中国临床药理学与治疗学》、《药学学报》等杂志的审稿人。

科研工作 :
近年代表性论文：[1] Shaoping Yin, Jue Huai, Xi Chen, Yong Yang, Xinxin Zhang, Yong Gan, Guangji Wangd, Xiaochen Gu, Juan Li*. Intracellular delivery and antitumor effects of a redox-responsive polymeric paclitaxel conjugate based on hyaluronic acid. Acta Biomaterialia. 2015,26:274-285. [IF: 6.025][2] Na Wu, Xinxin Zhang, FeiFei Li, Tao Zhang, Yong Gan*, Juan Li*. Spray-dried powders enhance vaginal siRNA delivery by potentially modulating the mucus molecular sieve structure. International Journal of Nanomedicine. 2015,10:5383-5396. [IF: 4.383][3] Lingqiang Xu#, Hua Yu#, Shaoping Yin, Ruixia Zhang, Yudan Zhou, Juan Li*. Liposome-based delivery systems for ginsenoside Rh2: in vitro and in vivo comparisons. Journal of Nanoparticle Research. 2015,17:415-428. [IF: 2.184][4] Xinxin Zhang#, Feifei Li#, Shiyan Guo, Xi Chen, Xiaoli Wang, Juan Li*, Yong Gan*. Biofunctionalized polymer-lipid supported mesoporous silica nanoparticles for release of chemotherapeutics in multidrug resistant cancer cells. Biomaterials. 2014,35: 3650-3665. [IF: 8.312][5] Shaoping Yin, Juan Li*, Nannan Li, Guangji Wang, Xiaochen Gu. Preparation and characterization of long-circulating PELMD/mPEG–PLGA-mixed micelles for 10-hydroxycamptothecin. Journal of Nanoparticle Research. 2014,16:2274-2288. [IF: 2.278][6] Hongzhi Qiao#, Juan Li#*, Yang Wang, Qineng Ping, Guangji Wang, Xiaochen Gu. Synthesis and characterization of multi-functional linear-dendritic block copolymer for intracellular delivery of antitumor drugs. International Journal of Pharmaceutics. 2013,452:363-373. (#co-first author) [IF: 3.785][7] Yanlei Zhao#, Juan Li#*, Hua Yu, Guangji Wang**. Synthesis and characterization of a novel polydepsipeptide contained tri-block copolymer (mPEG-PLLA-PMMD) as self-assembly micelle delivery system for paclitaxel. International Journal of Pharmaceutics. 2012 ,430:282-291. (#co-first author) [IF: 3.458][8] Juan Li*, Hua Yu, Shuai Li , Guangji Wang. Enhanced distribution and extended elimination of glycyrrhetinic acid in mice liver by mPEG-PLA modified (mPEGylated) liposome. Journal of Pharmaceutical and Biomedical Analysis. 2010,51:1147-1153. [IF: 2.78][9] Yuan Xie, Haiping Hao, An Kang, Yan Liang, Tong Xie, Shiqing Sun, Chen Dai, Xiao Zheng, LinXie, Juan Li**, Guangji Wang*. Integral pharmacokinetics of multiple lignan components in normal, CCl4-induced hepatic injury and hepatoprotective agents pretreated rats and correlations with hepatic injury biomarkers. Journal of Ethnopharmacology . 2010,131:290-299. (*corresponding author) [IF:2.58][10] Yang Lu, Juan Li*, Guang Ji Wang. In vitro and in vivo evaluation of mPEG-PLA modified liposomes loaded glycyrrhetinic acid. International Journal of Pharmaceutics . 2008,356:274-281. (*corresponding author) [IF: 3.01]