导师姓名：靳明亮
性别：
人气指数：149

所属院校：西北工业大学
所属院系：生命学院
职称：副教授
导师类型：
招生专业：生物学


通讯方式 :
电子邮件：mljin@nwpu.edu.cn


个人简述 :
2014-2015西北工业大学优秀教学成果一等奖;2013-2014西北工业大学优秀教学成果二等奖。

科研工作 :
2011年7月至2011年8月，美国密苏里州立大学哥伦比亚分校，访问学者；2011年7月至2013年6月，西北工业大学生命学院，航空宇航科学与技术博士后流动站，博士后；2013年6月至2014年4月，西北工业大学生命学院，讲师；2014年4月至今，西北工业大学生命学院，副教授；2015年9月2017年2月，加拿大阿尔伯塔大学，访问学者。 主持的科研项目：?1.?国家自然科学基金青年基金：白术多糖对断奶应激诱导肠粘膜屏障损伤的调控作用及机制研究，2018-2020，项目编号：**。2. GF科技创新TQ项目：应用于******技术和装置研究，2017-2019，项目编号：17-****-01。3. 陕西省自然科学基金面上项目：基于微生物区系研究模拟失重对肠黏膜屏障功能的影响，2017-2018，项目编号：2017JM3025。4.?中央高校基本科研业务费科研资助项目：白术多糖对模拟失重诱导肠黏膜屏障功能障碍的调控作用及机制研究，2017-2018，项目编号：**zy055。5.?中国博士后科学基金特别资助项目：基于Toll样受体通路研究模拟失重对肠道免疫功能的影响，2013~2014，项目编号：2012T50821。6. International Foundation for Science：Preparation, structural characterization and antiviral activities of sulfated polysaccharides from?Astragalus membranaceus，2012~2014，项目编号：F/5206-1。?7.?中国博士后科学基金面上项目：模拟微重力环境下灵芝多糖硫酸酯化衍生物对肠道免疫功能的调控及其机理研究，2011~2013，项目编号：2011M501481。?8.?中央高校基本科研业务费科研资助项目：肠道微生态在模拟失重诱导肠黏膜损伤中的作用及机制研究，2014-2016，项目编号：**JKY15001。@font-face {"宋体"}@font-face {"Cambria Math"}@font-face {"@宋体"}p.MsoNormal, li.MsoNormal, div.MsoNormal { text-align: justify"Times New Roman" }.MsoChpDefault { }div.WordSection1 { page: WordSection1 } 发表学术论文:[1].Jin, M.L., Zhu, Y.M., Shao, D.Y., Zhao, K., Xu, C.L.,Li, Q., Yang, H., Huang, Q.S., Shi, J.L. Effects of polysaccharide from myceliaof Ganoderma lucidum on intestinalbarrier functions of rats. InternationalJournal of Biological Macromolecules. 2017, 94: 1-9.[2].Xu,C., Guo, Y., Qiao, X., Shang, X., Niu, W., Jin,M. Design, recombinant fusion expression and 1 biological evaluation ofvasoactive intestinal peptide 2 analogue as novel antimicrobial agent. Molecules. 2017, 22: 1963.(Co-corresponding Author)[3].Zhao,K., Jin, M.L., Chen, Q., Zheng, P.S. Polysaccharides produced by Enterobactercloacae induce apoptosis in cervical cancer cells. International Journalof Biological Macromolecules. 2015, 72: 960-964. (Co-first Author)[4].Jin, M.L.,Wang, Y.M., Huang, M., Lu, Z.Q., Wang, Y.Z. Sulphation can enhance theantioxidant activity of polysaccharides produced by Enterobacter cloacaeZ0206. Carbohydrate Polymers. 2014, 99: 624-629.[5].Jin, M.L.,Zhao, K., Huang, Q.S., Shang, P. Structural features and biological activitiesof the polysaccharides from Astragalus membranaceus. InternationalJournal of Biological Macromolecules. 2014, 64: 257-266.[6].Jin, M.L.,Huang, Q.S., Zhao, K., Shang, P. Biological activities and potential healthbenefit effects of polysaccharides isolated from Lycium barbarum L. InternationalJournal of Biological Macromolecules. 2013, 54: 16-23.[7].Jin, M.L.,Zhao, K., Huang, Q.S., Shang, P. Preparation, structure and biologicalactivities of exopolysaccharides produced by Enterobacter cloacae. AsianJournal of Chemistry. 2013, 25: 9101-9104.[8].Jin, M.L.,Zhao, K., Huang, Q.S., Xu, C.L., Shang, P. Isolation, structure andbioactivities of the polysaccharides from Angelica sinensis (Oliv.)Diels: A review. Carbohydrate Polymers. 2012, 89: 713-722.[9].Jin, M.L.,Lu, Z.Q., Huang, M., Wang, Y.M., Wang, Y.Z. Effect of Se-enrichedpolysaccharides produced by Enterobacter cloacae Z0206 onalloxan-induced diabetic mice. International Journal of BiologicalMacromolecules. 2012, 50: 348-352.[10].Jin, M.L., Lu, Z.Q., Huang, M., Wang, Y.M., Wang, Y.Z.Sulfated modification and antioxidant activity of exopolysaccahrides producedby Enterobacter cloacae Z0206. International Journal of BiologicalMacromolecules. 2011, 48: 607-612.[11].Jin, M.L., Wang, Y.M., Huang, M., Lu, Z.Q., Wang, Y.Z.Optimization of culture medium for exo-polysaccharide production by Enterobactercloacae Z0206 using response surface methodology. Asian Journal ofChemistry. 2011, 23: 3799-3802.[12].Jin, M.L., Wang, Y.M., Xu, C.L., Lu, Z.Q., Huang, M.,Wang, Y.Z. Preparation and biological activities of an exopolysaccharideproduced by Enterobacter cloacae Z0206. Carbohydrate Polymers.2010, 81: 607-611.[13].Arrieta, M.C., Arevalo, A., Stiemsma, L.,Dimitriu, P., Chico, M.E., Loor, S., Vaca, M., Boutin, R.C.T., Morien, E., Jin, M., Turvey, S.E., Walter, J.,Parfrey, L.W., Cooper, P.J., Finlay, B. Associations between infant fungal andbacterial dysbiosis and childhood atopic wheeze in a non-industrializedsetting. Journal of Allergy and ClinicalImmunology. (In Press, DOI: org/10.1016/j.jaci.2017.08.041)[14].Riaz Rajok, M.S., Jin, M., Zhao, H., Li, Q., Shao, D., Jiang, C., Huang, Q., Yang,H., Shi, J., Hussain, N. Functional characterization and biotechnologicalpotential of exopolysaccharide produced by Lactobacillusrhamnosus strains isolated from human breast milk. LWT-Food Science and Technology. 2018, 89: 638-647.[15].Deehan, E.C., Duar, R.M., Armet, A.M.,Perez-Mu？oz, M.E., Jin, M., Walter,J. Modulation of the gastrointestinal microbiome with nondigestible fermentablecarbohydrates to improve human health. MicrobiologySpectrum. 2017, 5(5): BAD-0019-2017.[16].Zhao, X., Zhou, L., Riaz Rajoka, M.S., Yan, L.,Jiang, C., Shao, D., Zhu, J., Shi, J., Huang, Q., Yang, H., Jin, M. Fungal silver nanoparticles: synthesis,application and challenges. CriticalReviews in Biotechnology. 2017, 18: 1-19.[17].Li, J., Rajoka, W.S.R., Shao, D., Jiang, C., Jin, M., Huang, Q., Yang, H., Shi, J.Strategies to increase the efficacy of using gut microbiota for the modulationof obesity. Obesity Reviews. 2017, 18:1260-1271.[18].Riaz Rajoka, M.S., Shi, J., Zhu, J., Shao, D.,Huang, Q., Yang, H., Jin, M.Capacity of lactic acid bacteria in immunity enhancement and cancer prevention.Applied Microbiology and Biotechnology.2017, 101: 35-45.[19].Shao, D., Yao, L., Riaz, M.S., Zhu, J., Shi,J., Jin, M., Huang, Q., Yang, H.Simulated microgravity affects some biological characteristics of Lactobacillusacidophilus. Applied Microbiology andBiotechnology. 2017, 101: 3439-3449.[20].Zhao, H., Shao, D., Jiang, C., Shi, J., Li, Q.,Huang, Q., Rajok, M.S.R., Yang, H., Jin,M. Biological activity of lipopeptides from Bacillus. Applied Microbiology and Biotechnology. 2017, 101: 5951-5960.[21].Li, Q., Zhang, Y., Shi, J.L., Wang, Y.L., Zhao,H.B., Shao, D.Y., Huang, Q.S., Yang, H., Jin,M.L. Mechanism and anticancer activity of the metabolites of the endophyticfungi Eucommia ulmoides Oliv. Anti-cancer Agents in Medicinal Chemistry.2017, 17: 982-989.[22].Shao, D., Wang, Y., Huang, Q., Shi, J., Yang,H., Pan, Z., Jin, M., Zhao, H., Xu,X. Cholesterol-lowering effects and mechanisms in view of bile acid pathway ofresveratrol and resveratrol glucuronides. Journalof Food Science. 2016, 81: H2841-H2848.[23].Lu, Y., Shao, D., Shi, J., Huang, Q., Yang, H.,Jin, M. Strategies for enhancingresveratrol production and the expression of pathway enzymes. Applied Microbiology and Biotechnology.2016, 100: 7407-7421.[24].Xie, J.H., Tang, W., Jin, M.L., Li, J.E., Xie, M.Y. Recent advances in bioactivepolysaccharides from Lycium barbarumL., Zizyphus jujuba Mill, Plantago spp., and Morus spp.: Structures and functionalities. Food Hydrocolloid. 2016, 60: 148-160.[25].Xie, J.H., Jin, M.L., Morris, G.A., Zha,X.Q., Chen, H.Q., Yi, Y., Li, J.E., Wang, Z.J., Gao, J., Nie, S.P., Shang, P.,Xie, M.Y. Advances on bioactive polysaccharides from medicinal plants. CriticalReviews in Food Science and Nutrition. 2016, 56(S1): S60-S84.[26].Yang, H., Tang, R.H., Li, J., Liu, Y.X., Ye,L.J., Shao, D.Y., Jin, M.L., Huang, Q.S., Shi, J.L. A new Ex Vivo methodfor effective expansion and activation of human natural killer cells foranti-tumor immunotherapy. CellBiochemistry and Biophysics. 2015, 73: 723-729.[27].Yang, H., Liu, Y.X., Tang, R.H., Shao, D.Y.,Li, J., Ye, L.J., Jin, M.L., Huang, Q.S., Shi, J.L. Cell signaling inthe interaction between pathogenic bacteria and immune cells. Frontiers inBioscience-Landmark. 2015, 20: 1029-1035.[28].Yang, H., Tang, R.H., Li, J., Li, J., Liu,Y.X., Ye, L.J., Shao, D.Y., Jin, M.L., Huang, Q.S., Shi, J.L. Changes ofcytoskeleton affect T cell biological behaviors. Frontiers inBioscience-Landmark. 2015, 20: 829-837.[29].Yang, H., Li, J., Tang, R.H., Li, J., Liu,Y.X., Ye, L.J., Shao, D.Y., Jin, M.L., Huang, Q.S., Shi, J.L. Theaspartyl (asparaginyl) beta-hydroxylase in carcinomas. Frontiers inBioscience-Landmark. 2015, 20: 902-909.[30].Huyan, T., Li, Q., Yang, H., Jin, M.L.,Zhang, M.J., Ye, L.J., Li, J., Huang, Q.S., Yin, D.C. Protective effect ofpolysaccharides on simulated microgravity-induced functional inhibition ofhuman NK cells. Carbohydrate Polymers. 2014, 101: 819-827.[31].Lu, Z.Q., Jin, M.L., Huang, M., Wang,Y.M., Wang, Y.Z. Bioactivity of selenium-enriched exopolysaccharides producedby Enterobacter cloacae Z0206 in broilers. Carbohydrate Polymers.2013, 96: 131-136.[32].Xu, C.L., Wang, Y.Z., Jin, M.L., Yang,X.Q. Preparation, characterization and immunomodulatory activity ofselenium-enriched exopolysaccharide produced by bacterium Enterobactercloacae Z0206. Bioresource Technology. 2009, 100: 2095-2097.?发表会议论文：[1].Jin, M.L.,Shang, P. Effects of simulated weightlessness on the intestinal mucosal barrierfunctions of rats. Proceeding of the 19th International Academy of Astronautics (IAA)Humans in Space. Jul. 2013. Cologne, Germany.[2].Jin, M.L.,Wang, Y.M., Lu, Z.Q., Huang, M., Xu, C.L., Wang, Y.Z. Isolation,characterization and antioxidant activity of an exopolysaccharide produced byEnterobacter cloacae Z0206. Proceedings of ADSA-CSAS-ASAS Joint AnnualMeeting. Jul. 2010. Denver, USA.[3].Jin, M.L.,Wang, Y.Z., Yang, X.Q., Xu, C.L., Lu, Z.Q. Protective effect of polysaccharideproduced by Enterobacter cloacae Z0206 on cyclophosphamide-inducedsuppression of immune functions in mice. Proceedings of ADSA-CSAS-ASAS JointAnnual Meeting. Jul. 2009. Montreal, Canada.[4].Jin, M.L.,Wang, Y.Z., Xu, C.L., Yang, X.Q. Effect of enriched-Selenium exopolysaccharideand exopolysaccharide produced by Enterobacter cloacae Z0206 on immunefunction of immunosuppressed mice. Proceeding of the 13th Animal ScienceCongress of the Asian-Australasian Association of Animal Production Societies.Sep. 2008. Hanoi, Vietnam.参编著作：[1].Deehan,E.C., Duar, R.M., Armet, A.M., Perez-Munoz, M.E., Jin, M., Walter, J. Chapter 20: Modulation of the gastrointestinalmicrobiome with nondigestible fermentable carbohydrates to improve humanhealth. Bugs as Drugs: Therapeutic Microbes for the Prevention and Treatment ofDisease. ASM Press, 2018.

教育背景 :
2002.9-2006.6，南京农业大学动物科技学院，本科；2006.9-2011.6，浙江大学动物科学学院，博士。