黄 健: 博士，副教授

E-Mail jhuang@bjmu.edu.cn

地址北京市海淀区学院路38号药学院306室 邮编100191

1995 年毕业于兰州大学，获理学学士学位；

1998年毕业于兰州大学，获理学硕士学位；

2005年毕业于北京大学，获药物化学博士学位；

2005年至今在北京大学药学院化学生物学系无机化学专业。

研究方向：细胞无机化学和无机药物化学；研究骨质疏松的发病机制和药物预防；研究药物对前列腺癌骨转移的抑制。

近几年发表文章:

1.王芃, 黄健*, 张天蓝, 王夔*.氯化镧抑制人转移型雄性激素非依赖性前列腺癌细胞DU145的生长和迁移. 科学通报，2010, 55(23): 2289-2295.

2.Jian huang, Xi. Wang, Tian-lan Zhang, Kui Wang. Alterations of ovariectomized rat bone and impact of non-collagenous proteins on mineralization. Joint Bone Spine, 2009, 76(2):176-183

3.Shi Yanling, Wang Liwen, Huang Jian, Gou Baodi, Zhang Tianlan, Wang Kui. Lanthanum Suppresses Osteoblastic Differentiation Via Pertussis Toxin-Sensitive G Protein Signaling in Rat Vascular Smooth Muscle Cells. Journal of Cellular Biochemistry 2009, 108: 1184-1191

4.Wang Chen-Guang, Liao Jia-Wang, Gou Bao-Di, Huang Jian, Tang Rui-Kang, Tao Jin-Hui, Zhang Tian-Lan, Wang Kui. Crystallization at Multiple Sites inside Particles of Amorphous Calcium Phosphate. Crystal Growth Design, 2009, 9: 2620–2626.

5.Xi Wang, Jian Huang*, Tianlan Zhang , Kui Wang. Cytoskeleton reorganization and FAK phosphorylation are involved in lanthanum (III)-promoted proliferation and differentiation in rat osteoblasts. Progress in Nature Science

2009,19: 331-335

6.Xi Wang, Lan Yuan, Jian Huang*, Tian-Lan Zhang*, Kui Wang. Lanthanum Enhances in vitro Osteoblast Differentiation via Pertussis Toxin-sensitive Gi Protein and ERK Signaling Pathway. Journal of Cellular Biochemistry 2008, 105: 1307-1315

7.王熙, 黄健*, 张天蓝, 王夔. La3 + 通过重组细胞骨架影响大鼠成骨细胞增殖、分化, 自然科学进展, 2008, 18: 1053-1057

8.Jian huang, Lan Yuan, Xi. Wang, Tian-lan Zhang, Kui Wang. Icarin and its glycosides enhance osteoblastic ,but suppress osteoclastic, differentiation and activity in vitro. Life Sciences, 2007,81(10):832-840

9.Jian Huang, Jina-Chao Zhang, Tian-Lan Zhang, Kui Wang. Icariin suppresses bone resorption activity of rabbit osteoclasts in vitro. Chinese Science Bulletin, 2007, 52(7):890-895. ‘

10.Jian Huang, Tian-Lan Zhang, Shan-jin Xu, Kui Wang, Jing Zhang, Ya-Ning Xie.. Effects of Lanthanum on Composition, Crystal Size and Lattice Structure of Femur Bone Mineral of Wistar Rats. Calcif Tissue Int， 2006 78（4）:241–247

11.黄健, 张金超,张天蓝, 许善锦,王夔. 淫羊霍苷对破骨细胞骨吸收功能的影响及其作用机制研究. 科学通报, 2006, 51(24):2851-2856