导师姓名：刘伟
性别：男
人气指数：43

所属院校：天津科技大学
所属院系：化工与材料学院
职称：副教授
导师类型：
招生专业：生物化工
研究领域： 药物化学及化学生物学；有机合成方法学及电化学合成
研究领域： 药物化学及化学生物学；有机合成方法学及电化学合成 [收起]




通讯方式 :
办公电话：**
电子邮件：liuwei2006@tust.edu.cn


科研工作 :
自2000年至今，已在国内外学术刊物以第一作者通讯作者或第二作者（通讯导师为第一作者）发表SCI收录论文20余篇。其中包括：RAPID COMMUN MASS SP INT J MASS SPECTROM APPL ORGANOMET CHEM J ORGANOMET CHEM BULL CHEM SOC JPN BIOORGAN MED CHEM J HETEROCYCLE CHEM NUCLEOS NUCLEOT NUCL等国际杂志。在天津科技大学期间论文发表情况如下：(1) Wei Liu* Yanling Guo Cong Han Shaoling Cheng 1-(4-Nitrophenyl)pyrrolidine-2-carboxamide Acta Crystallographica Section E 2007 6(5) o2778-o2779.(2) Wei Liu* Yanling Guo Cong Han Xiaonan Huang Characteristic fragmentation behavior of 5-[1-aryl-1H-pyrrol-2-yl]-1H-tetrazole by electrospray ionization tandem mass spectrometry Life Science Journal-ACTA ZHEN 2008 5(2) 25-29.(3) Wei Liu* Yanting Tang Yu Guo Bo Sun Hemin Zhu Yanyan Xiao Dandan Dong Cheng Yang Synthesis characterization and bioactivity determination of ferrocenyl urea derivatives Applied Organometallic Chemistry 2012 26 189-193.(4) Wei Liu* Lin Zhang Honggang Zhou Cheng Yang Zhiwei Miao Yufen Zhao Synthesis of Novel Nucleoside Analogue Phosphorothioamidate Prodrugs and in vitro Anticancer Evaluation Against RKO Human Colon Carcinoma Cells Nucleosides Nucleotides and Nucleic Acids 2013 32 161-173.(5) Dandan Dong Yanyan Xiao Wei Liu* Honggang Zhou Cheng Yang. Progress in Kinase Aurora-B and its inhibitors Acta Pharmaceutica Sinica 2013 48 457-465.(6) Dazhi Liu Zhen Tian Zhihui Yan Lixin Wu Yan Ma Quan Wang Wei Liu* Honggang Zhou Cheng Yang Design synthesis and evaluation of 1 2-benzisothiazol-3-one derivatives as potent caspase-3 inhibitors Bioorganic & Medicinal Chemistry 2013 21 2960-2967.(7) Sun Yuan-Pei Zhang Ning Wang Jian Guo Yu Sun Bo Liu Wei* Zhou Hong-Gang Yang Cheng. Synthesis and Biological Evaluation of quinolinone compounds as SARS CoV 3CLpro inhibitors. Chinese J. Chem. 2013 31 1199-1206.(8) 朱贺敏，孙晓晓，刘伟*，周红刚，杨诚. 靶标Aurora A激酶结构功能与抑制剂研究进展. 中国药学杂志，2013，48（10），753-758.(9) Sun Xiao-xiao Sun Tao Wang Tai-yi Zhang Yan Liu Hui-juan Wang Quan Niu Guo-jun Liu Wei* Zhou Hong-gang Yang Cheng. Synthesis and Characterization of Pyrazoleanthrone Derivatives as Aurora A Kinase Inhibitors. Chem. Res. Chin. Univ. 2013 29 6: 1098-1103.(10) Wei Liu* He-Min Zhu Guo-Jun Niu En-Zhi Shi Jie Chen Bo Sun Wei-Qiang Chen Hong-Gang Zhou Cheng Yang. Synthesis modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors. Bioorganic & Medicinal Chemistry 2014 22 292-302.(11) Lixin Wu Meiqi Lu Zhihui Yan Xiaobin Tang Bo Sun Wei Liu* Honggang Zhou Cheng Yang. 1 2-Benzisothiazol-3-one derivatives as a novel class of small-molecule caspase-3 inhibitors. Bioorganic & Medicinal Chemistry 2014 22 2416-2426.(12) Zhenghui Li Yang Pan Weilong Zhong Yunpeng Zhu Yongle Zhao Lixin Li Wei Liu* Honggang Zhou Cheng Yang. Synthesis and evaluation of N-acyl-substituted 1 2-benzisothiazol-3-one derivatives as caspase-3 inhibitors. Bioorganic & Medicinal Chemistry 2014 22 6735-6745.(13) Zhenfei Guo Zhihui Yan Xiaowei Zhou Quan Wang Meiqi Lu Wei Liu* Honggang Zhou Cheng Yang Edward J. McClain Synthesis and biological evaluation of novel 1 2-benzisothiazol-3-one-derived 1 2 3-triazoles as caspase-3 inhibitors. Med Chem Res 2015 24: 1814-1829.(14) Wei Zhao Wei Liu*. Progresses of Weinreb Amides in Organic Synthesis. Chinese Journal of Organic Chemistry 2015 35 55-69.(15) Tang Xiaobin Li Zhenghui Li Yonghong Liu Wei* Yu Peng Li Lixin Guo Yu and Yang Cheng. Synthesis and Biological Evaluation of Novel Saccharin Derivatives Containing 1 2 3-Triazole Moiety. Chem. Res. Chin. Univ. 2015 31(1) 71-77.(16) Zhou Xiaowei Tang Yanting Sang Feng Wang Jinghan Li lixin Zhang Xiuli Liu Wei* Dai Yujie. Synthesis and Biological Evaluation of Phosphotyrosyl Mimetic as a Novel PTP1B Inhibitor. Chinese Journal of Organic Chemistry 2015 35(6) 1363-1369.