导师姓名：束刚
性别：男
人气指数：90

所属院校：华南农业大学
所属院系：动物科学学院
职称：教授
导师类型：硕导/博导
招生专业：生理学、动物营养与饲料科学、畜牧 、畜牧（非全日制）
研究领域： （1）代谢中间产物营养生理；（2）采食与能量代谢。
研究领域： （1）代谢中间产物营养生理；（2）采食与能量代谢。 [收起]




通讯方式 :
电子邮件：shugang@scau.edu.cn


个人简述 :
个人简介
束刚，男，1979年生，博士，教授，华南农业大学动物科学学院教师，动物营养与饲料科学系副系主任。畜牧兽医学会动物生理生化分会和广东省生理学会理事。2003年7月至今任教于华南农业大学动物科学学院，主要从事动物营养生理的教学与科研工作，2014年入选广东省优秀青年教师培养计划，2014-2015年在美国贝勒医学院儿童营养中心访问学者。2017年入选华南农业大学“丁颖人才支持工程”。研究方向包括：（1）代谢中间产物营养生理；（2）采食与能量代谢。本人先后主持国家自然科学基金3项，广东省自然科学基金1项和省部产学研及企业横向课题各1项；973和十三五重点研发骨干各1项；参加国家自然科学基金3项、广东省自然科学基金团队项目和国家“973”子项目等多项国家和省部级项目。在Cellreports(2016,2017),Metabolism(2017),FASEBJournal(2017),JournalofNutritionalBiochemistry,journalofagricultureandfoodchemistry,JournalofAnimalScience,Oncotarget和Scientificreports等杂志发表SCI论文40余篇，参编教材2部，参译1部，申报专利3项。
获奖荣誉
2014广东省优青培养对象
2017华南农业大学“丁颖人才支持工程”

科研工作 :
工作经历
2003.7至今华南农业大学动物科学学院
社会、学会及学术兼职
畜牧兽医学会动物生理生化分会理事
广东省生理学会理事
科研项目
1.广东省高等学校优秀青年教师培养计划（2015年-2017年）。
2.国家自然科学基金面上项目（**），猪下丘脑TLR4炎症通路在食欲调节中的作用及其分子机制，2016.01-2019.12，79.2万元，在研，主持。
3.国家自然基金面上项目（**），Syndecan-3调节猪采食的作用机制及其营养调控。2015/01-2018/12、88万元、在研、参加。
4.国家重点基础研究发展计划（973计划）课题（2013CB127306）、猪利用氮营养素的机制及营养调控。2013/01-2017/12、88万元、在研、课题骨干。
5.广东省自然科学基金重点项目（S**48）、SCD1-1与DGAT-2调控猪肌肉脂肪酸组成的分子机制研究。2012/10-2015/10、30万元、在研、参加。
6.广东省高等学校“千百十工程”第七批培养对象（2012年-2015年）
7.广东省教育部产学研结合项目，生产优质安全猪肉的饲料配制技术研究与推广应用、2011/03-2013/03、7万元、已结题、主持。
8.国家自然科学基金（**）、猪FAT特异性调控肌内脂肪沉积的分子机制、2010/1-2012/12、30万元、已结题、主持。
9.国家自然科学青年基金（**）、鸡脂肪酸转运蛋白（FATP1）参与体脂分配的分子机制研究、2006/1-2008/12、25万元、已结题、主持。
发表论文
JingrenXu,CanjunZhu,MengyuanZhang,QingchunTong,XiaojuanWan,ZhengruiLiao,XingcaiCai,YaqiongXu,YexianYuan,LinaWang,XiaotongZhu,SongboWang,PingGao,QianyunXi,YongXu,QingyanJiangandGangShu(correspondingauthor).ArginineReversesGrowthHormoneResistancethroughtheInhibitionofToll-likeReceptor4-MediatedInflammatoryPathway.Metabolism(accepted)（IF2016=5.78）
YuanY,XuY,XuJ,LiangB,CaiX,ZhuC,WangL,WangS,ZhuX,GaoP,WangX,ZhangY,JiangQ,ShuG(correspondingauthor).SuccinatepromotesskeletalmuscleproteinsynthesisviaErk1/2signalingpathway.MolMedRep.2017Sep20.doi:10.3892/mmr.2017.7554.
CaiX,YuanY,LiaoZ,XingK,ZhuC,XuY,YuL,WangL,WangS,ZhuX,GaoP,ZhangY,JiangQ,XuP,ShuG(correspondingauthor).α-KetoglutaratepreventsskeletalmuscleproteindegradationandmuscleatrophythroughPHD3/ADRB2pathway.FASEBJ.2017Sep22.pii:fj.**R.（IF2016=5.5）
CanjunZhu1,4,PingwenXu2,4,YanlinHe2,4,YexianYuan1,TaoWang1,XingcaiCai1,LuluYu1,LiusongYang1,JunguoWu1,LinaWang1,XiaotongZhu1,SongboWang1,PingGao1,QianyunXi1,YongliangZhang1,YongXu2,3,*,QingyanJiang1,*andGangShu1,*(correspondingauthor).HeparinincreasesfoodintakethroughAgRPneurons.CellRep.2017,Sep520(10),p2455–2467.(IF2016=8.28)
HeY#,ShuG#(co-firstauthor),YangY,XuP,XiaY,WangC,SaitoK,HintonAJr,YanX,LiuC,WuQ,TongQ,XuY.ASmallPotassiumCurrentinAgRP/NPYNeuronsRegulatesFeedingBehaviorandEnergyMetabolism.CellRep.2016Nov817(7):1807-1818.(IF2016=8.28)
LiusongYang1,*,LinaWang1,*,CanjunZhu1,JunguoWu1,YexianYuan1,LuluYu1,YaqiongXu1,JingrenXu1,TaoWang1,ZhengruiLiao1,SongboWang1,3,XiaotongZhu1,PingGao1,YongliangZhang1,2,XiuqiWang2,3,QingyanJiang1,3andGangShu1,2,3(correspondingauthor).Laminarincounteractsdiet-inducedobesityassociatedwithglucagon-likepeptide-1secretion.2017.https://doi.org/10.18632/oncotarget.19957.(IF2016=5.17)
WuJ,ZhuC,YangL,WangZ,WangL,WangS,GaoP,ZhangY,JiangQ,ZhuX,ShuG(correspondingauthor).N-Oleoylglycine-InducedHyperphagiaIsAssociatedwiththeActivationofAgouti-RelatedProtein(AgRP)NeuronbyCannabinoidReceptorType1(CB1R).JAgricFoodChem.2017Feb865(5):1051-1057.(IF2016=3.15)
WangS,WangG,ZhangM,ZhuangL,WanX,XuJ,WangL,ZhuX,GaoP,XiQ,ZhangY,ShuG(co-correspondingsauthor),JiangQ*.ThedipeptidePro-AsppromotesIGF-1secretionandexpressioninhepatocytesbyenhancingJAK2/STAT5signalingpathway.MolCellEndocrinol.2016Nov15436:204-10.(IF2016=3.75)
CaiX,ZhuC,XuY,JingY,YuanY,WangL,WangS,ZhuX,GaoP,ZhangY,JiangQ,ShuG(correspondingauthor).Alpha-ketoglutaratepromotesskeletalmusclehypertrophyandproteinsynthesisthroughAkt/mTORsignalingpathways.SciRep.2016May266:26802.(IF2016=4.26)
JingY,CaiX,XuY,ZhuC,WangL,WangS,ZhuX,GaoP,ZhangY,JiangQ,ShuG(correspondingauthor).α-LipoicAcidsPromotetheProteinSynthesisofC2C12MyotubesbytheTLR2/PI3KSignalingPathway.JAgricFoodChem.2016Mar264(8):1720-9.（IF2016=3.15）
WangS,XiangN,YangL,ZhuC,ZhuX,WangL,GaoP,XiQ,ZhangY,ShuG(co-correspondingauthor),JiangQ.LinoleicacidandstearicacidelicitoppositeeffectsonAgRPexpressionandsecretionviaTLR4-dependentsignalingpathwaysinimmortalizedhypothalamicN38cells.BiochemBiophysResCommun.2016Mar18471(4):566-71.
YanC,HeY,XuY,ShuG,WangC,YangY,SaitoK,XuP,HintonAOJr,YanX,YuL,WuQ,TsoP,TongQ,XuY.ApolipoproteinA-IVInhibitsAgRP/NPYNeuronsandActivatesPOMCNeuronsintheArcuateNucleus.Neuroendocrinology.2015Aug25.
GangShu,LuNS,ZhuXT,XuY,DuMQ,XieQP,ZhuCJ,XuQ,WangSB,WangLN,GaoP,XiQY,ZhangYL,JiangQY.Phloretinpromotesadipocytedifferentiationinvitroandimprovesglucosehomeostasisinvivo.JournalofNutritionalBiochemistry.2014Dec25(12):1296-308.
GangShu*,1,Xing-LingFang,Sheng-FengChen*,Zhi-QiZhang*,Qing-JieZeng*,LinDeng*,Jian-LongPeng*,Jian-JianYu*,Li-NaWang*,Xiao-TongZhu*,Song-BoWang*,PingGao*,andQing-yanJiang.Differentialgeneexpressionpatterninhypothalamusofchickensduringfasting-inducedmetabolicreprogramming:functionsofglucoseandlipidmetabolisminthefeedintakeofchickens.PoultryScience.2014Nov93(11):2841-54.
ZhangZQ,ShuG,ZhuXT,WangLN,FuQ,HouLJ,WangSB,GaoP,XiQY,ZhangYL,YuL,LvJR,JiangQY.Isolationandcharacterizationofporcinecircumvallatepapillaecells.ActaHistochem.2014Oct116(8):1313-22.
ZhiqiZhang1,?GangShu1,?(co-firstauthor)XiaotongZhu1,JunmingGuo1,HanCai1,SongboWang1,LinaWang1,PingGao1,QianyunXi1,YongliangZhang1,LiYuan2,QingyanJiang1.*Effectofdiacylglycerolacyltransferase2overexpressionin3T3-L1isassociatedtoanincreaseinmono-unsaturatedfattyacidaccumulation.JournalofAnimalScienceandBiotechnology.2014May285(1):29.
Xing-LingFang*,GangShu*(co-firstauthor),Jian-JianYu*,Li-NaWang,JingYang,Qing-JieZeng,XiaoCheng,Zhi-QiZhang,Song-BoWang,PingGao,Xiao-TongZhu,Qian-YuXi,Yong-LiangZhang,Qing-YanJiang§.TheanorexigeniceffectofserotoninismediatedbythegenerationofNADPHOxidase-DependentROS.PLoSOne.20138(1):e53142.doi:10.1371/journal.pone.**.
SongboWang,GuixuanZhou,GangShu,LinaWang,XiaotongZhu,PingGao,QianyunXi,YongliangZhang,LiYuan,QingyanJiang.GlucoseUtilization,LipidMetabolismandBMP-SmadSignalingPathwayofPorcineIntramuscularPreadipocytesComparedwithSubcutaneousPreadipocytes.CellularPhysiologyandBiochemistry,2013,31:981-996.
"KaifanYu*1,GangShu*1(co-firstauthor),Fangfangyuan1,XiaotongZhu1,PingGao1,SongboWang1,LinaWang1,QianyunXi1,ShouquanZhang1,YongliangZhang1,YanLi2,TongshanWu2,LiYuan3,QingyanJiang1",FattyAcidandTranscriptomeProfilingofLongissimusDorsiMusclesbetweenPigBreedsDifferinginMeatQuality,InternationalJournalofBiologicalSciences,2013,1449-2288,9(1):108-118.
JunmingGuo1*,GangShu1*(co-firstauthor),LihuaZhou1*,XiaotongZhu1,WeiyiLiao1,SongboWang1,JinzengYang3,GuixuanZhou1,QianyunXi1,PingGao1,YongliangZhang1,ShouquanZhang1,LiYuan2,andQingyanJiang1.SelectiveTransportofLongChainFattyAcidsbyFAT/CD36inSkeletalMuscleofBroilers.Animal.2012.DOI:10.1017/S**01619.
Xing-LingFang*,GangShu*(co-firstauthor),Jian-JianYu*,Li-NaWang,JingYang,Qing-JieZeng,XiaoCheng,Zhi-QiZhang,Song-BoWang,PingGao,Xiao-TongZhu,Qian-YuXi,Yong-LiangZhang,Qing-YanJiang§.TheanorexigeniceffectofserotoninismediatedbythegenerationofNADPHOxidase-DependentROS.PLoSOne.20138(1):e53142.doi:10.1371/journal.pone.**.Epub2013Jan9.
SongboWangGuixuanZhouGangShuLinaWangXiaotongZhuPingGaoQianyunXiYongliangZhangLiYuanQingyanJiang,GlucoseUtilization,LipidMetabolismandBMP-SmadSignalingPathwayofPorcineIntramuscularPreadipocytesComparedwithSubcutaneousPreadipocytes,CellularPhysiologyandBiochemistry,1015-8987,31:981-996,2013
"KaifanYu*1,GangShu*1,Fangfangyuan1,XiaotongZhu1,PingGao1,SongboWang1,LinaWang1,QianyunXi1,ShouquanZhang1,YongliangZhang1,YanLi2,TongshanWu2,LiYuan3,QingyanJiang1",FattyAcidandTranscriptomeProfilingofLongissimusDorsiMusclesbetweenPigBreedsDifferinginMeatQuality,InternationalJournalofBiologicalSciences,1449-2288,9(1):108-118,2013
Ya-FengZ,GangS,Xiao-TongZ,Zhi-QiZ,Xia-JingL,Song-BoW,Li-NaW,Yong-LiangZ,Qing-YanJ,Identificationofanintestine-specificpromoterandinducibleexpressionofbacterialalpha-galactosidaseinmammaliancellsbyalacoperonsystem,JournalofAnimalScienceandBiotechnology,2049-189,3(1):32,2012
Shu,G.,W.Y.Liao,J.Y.Feng,K.F.Yu,Y.F.Zhai,S.B.Wang,P.Khondowe,X.Q.Wang&Q.Y.Jiang(2011)Activeimmunizationoffattyacidtranslocasespecificallydecreasedvisceralfatdepositioninmalebroilers.PoultryScience,90,2557-2564.
Xin-LingFang,GangShu(co-firstauthor),,Zhi-QiZhang,Song-BoWang,Xiao-TongZhu,PingGao,Qian-YunXi,Yong-LiangZhang&Qing-YanJiang.Rolesofα-linolenicacidonIGF-IsecretionandGH/IGFsystemgeneexpressioninporcineprimaryhepatocytes.MolecularBiologyReports.2012.39:10987–10996.
Shu,G.,X.T.Zhu,X.Q.Wang,Y.Z.Song,Y.F.Bin,Y.L.Zhang,P.Gao&Q.Y.Jiang(2009)Identificationandgeneexpressionofporcinefattyacidtransportprotein1isoforms.JournalofAnimalPhysiologyandAnimalNutrition,93,439-446.
Luo,Z.F.,X.L.Fang,G.Shu(co-firstauthor),S.B.Wang,X.T.Zhu,P.Gao,L.L.Chen,C.Y.Chen,Q.Y.Xi,Y.L.Zhang&Q.Y.Jiang(2011)Sorbicacidimprovesgrowthperformanceandregulatesinsulin-likegrowthfactorsystemgeneexpressioninswine.JournalofAnimalScience,89,2356-2364.
Shu,G.,Q.Y.Jiang,X.T.Zhu,H.X.Zhang,P.Gao,Y.L.Zhang&X.Q.Wang(2008)Identificationofporcinefattyacidtranslocase:high-leveltranscriptinintramuscularfat.JournalofAnimalPhysiologyandAnimalNutrition,92,562-568.
Shu,G.,P.Gao,X.T.Zhu,Q.Y.Jiang,P.W.Xu,G.X.Zhou,F.W.Sun&W.L.Fu(2007)Effectsofglycyl-glutamineonthegrowthperformanceandlipiddepositioninYue-Huangbroilers.JournalofAnimalandFeedSciences,16,232-240.
Tang,S.-Q.,S.Gang,X.-T.Zhu,S.-B.Wang,G.Ping,X.-Q.Wang,Y.-L.Zhang&Q.-Y.Jiang(2009)EffectsofpGhrelinonCaspase-3ActivityandGeneExpressionofPorcinePredipocytesinCulture.ProgressinBiochemistryandBiophysics,36,897-903.
Xu,P.-w.,X.-l.Fang,G.Shu,X.-t.Zhu,Z.-f.Luo,Q.-y.Jiang,P.Gao&Y.-l.Zhang(2010)ProkaryoticExpressionofGly-GlnDipeptideandItsBioactiveAnalysis:ANovelMethodforShortPeptideProduction.AgriculturalSciencesinChina,9,736-744.
Wang,X.-q.,Y.Feng,G.Shu,Q.-y.Jiang,J.-p.Yang&Z.-f.Zhang(2011)EffectofDietarySupplementationwithHydrolyzedWheatGlutenonGrowthPerformance,CellImmunityandSerumBiochemicalIndicesofWeanedPiglets(Susscrofa).AgriculturalSciencesinChina,10,938-945.
Zhou,G.,S.Wang,Z.Wang,X.Zhu,G.Shu,W.Liao,K.Yu,P.Gao,Q.Xi,X.Wang,Y.Zhang,L.Yuan&Q.Jiang(2010)Globalcomparisonofgeneexpressionprofilesbetweenintramuscularandsubcutaneousadipocytesofneonatallandracepigusingmicroarray.MeatScience,86,440-450.
Li,H.,Q.Xi,Y.Xiong,X.Cheng,Q.Qi,L.Yang,G.Shu,S.Wang,L.Wang,P.Gao,X.Zhu,Q.Jiang,Y.Zhang&L.Yuan(2011)AComprehensiveExpressionProfileofMicroRNAsinPorcinePituitary.PloSone,6.
束刚*，冯嘉颖*，余凯凡，徐平稳，朱晓彤，高萍，王松波，习欠云，王修启，张永亮，江青艳。FAT/CD36融合蛋白的表达及其对腹脂沉积的特异性调控。中国农业科学2009,42(2)
林厦菁,朱晓彤,江青艳,束刚,叶绿醇对脂肪细胞分化及糖脂代谢的调节作用,动物营养学,24(10):1866-1870,2012
张志歧,束刚,江青艳,下丘脑对脂类的营养感应及其对食欲的影响,动物营养学报中国,25(7):1395-1405,2013
科研创新
江青艳、束刚等，《已二稀酸在制备改善猪肉品质的饲料添加剂方面的应用》，2010.5，中国，**.2
束刚、江青艳等，《叶绿醇在制备猪饲料添加剂方面的应用及猪饲料》，2013.6，中国，**4.6
束刚、江青艳等，《酮戊二酸在制备猪饲料添加剂方面的应用》，2015.9，中国**5.2

教育背景 :
1996安徽科技学院畜牧专业本科
2000南京农业大学动物生理生化专业硕士
2006华南农业大学动物营养与饲料科学博士