导师姓名：胡春
性别：男
人气指数：126

所属院校：沈阳药科大学
所属院系：制药工程学院
职称：教授
导师类型：硕导/博导
招生专业：有机化学、应用化学、药物化学、药学（药物化学方向）
研究领域： 研究方向一：杂环化合物的合成及生物活性研究;研究方向二：医药中间体的研究;研究方向三：金属... [展开]


研究领域： 研究方向一：杂环化合物的合成及生物活性研究;研究方向二：医药中间体的研究;研究方向三：金属有机化合物的合成及生物活性研究 [收起]




通讯方式 :
办公电话：**
电子邮件：chunhu1999@163.com
通讯地址：沈阳市沈河区文化路103号


个人简述 :
胡春，男，博士，教授。1985年毕业于江苏师范大学，获化学学士学位，1988年毕业于东北师范大学，获有机化学硕士学位，1999年毕业于沈阳药科大学，获药物化学博士学位，2014年在香港中文大学作为高级访问学者进修一年。1988年起在沈阳药科大学工作至今，1995被评为沈阳药科大学副教授，2000年晋升为教授，2002年被评为博士生导师。目前的主要研究方向有新药设计与合成、医药中间体的研究、杂环化合物的合成及生物活性研究、金属有机化合物的合成及生物活性研究等。作为课题负责人完成了国家自然科学基金项目3项，国家新药研究基金2项，国家重大科技专项1项。目前已在ARKIVOC, MedicinalChemistry, Heterocycles, Bioorganic & Medicinal Chemistry Letters, ChemicalResearch in Chinese Universities, Letters in Drug Design & Discovery,Chemico-Biological Interactions, Chinese Chemical Letters, Latin AmericanJournal of Pharmacy, Molecules等期刊发表论文100余篇，其中SCI收载30余篇。

科研工作 :
近年来发表代表性论文
1.ZHANG Lan, DENG Xinshan, WU Jiaofeng, MENGGuangpeng, LIU Congchong, CHEN Guzhou, ZHAO Qingchun, HU Chun*. Design,Synthesis and Biological Activities ofN-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal GrowthFactor Receptor Inhibitors and Anticancer Agents. Chemical Research in ChineseUniversities, 2017, 33(3): 365-372.2.Lan Zhang, Xin-Shan Deng, Chao Zhang, Guang-PengMeng, Jiao-Feng Wu, Xue-Song Li, Qing-Chun Zhao, Chun Hu*. Design, synthesisand cytotoxic evaluation of a novel series of benzo[d]thiazole-2-carboxamidederivatives as potential EGFR inhibitors. Medicinal Chemistry Research, 2017,26(9):2180-2189.3.Wenjing Ye, Xiao Xiao, Lan Wang, Shicheng Hou,Chun Hu*. Synthesis of mono- and binuclear Cu(ii) complexes bearingunsymmetrical bipyridine–pyrazole–amine ligand and their applications inazide–alkyne cycloaddition. Organometallics, 2017, 36 (11): 2116–2125.4.Bing SUN, Jin ZHANG , Xiu’e YIN, Yue XU, FurongZHANG, Yushu HUANG, Jinhui WANG, Guoqing WANG & Chun HU*. Synthesis,Characterization and Biological Activity of thieno[2,3-d]pyrimidine Derivativesas the Epidermal Growth Factor Receptor Inhibitors. Latin American Journal ofPharmacy, 2016, 35(3): 570-577.5.LI Han-Yue, HAN Yu, JIN Zhe, WANG Shi-Hui, LIXin-Zeng, LIU Si-Yu, HU Chun*. The Crystal Structure of3-(4-methoxyphenyl)-2-(4-methylbenzoyl)-6,7-dihydro-5H-furo[3,2-g]chromene.Chinese Journal of Structural Chemistry, 2016, 35(4): 545-549.6.Gang Li, Liang Zhao, Peng Yang, Zhaozheng Yang,Zhangmin Tian, Yan Chen, Hongyan Shen, and Chun Hu*. Engineering 1,3-AlternateCalixcarbazole for Recognition and Sensing of Bisphenol F in Water. Anal Chem.2016 , 88(21):10751-10756.7.Xiao-ping Liu, Hui-lan Xu, Rui Sun, Xue Li,Bao-hua Hu, Chun Hu*. Synthesis and Characterization of Two Impurities inEsomeprazole, an Antiulcerative Drug. Latin American Journal of Pharmacy, 2015,34(6): 1265–1268.8.Bing Sun, Xiu’e Yin, Jin Zhang, Jian Huang, YueXu, Furong Zhang, Jinhui Wang, Guoqing qing Wang, Chun Hu*. Synthesis,Characterization and Biological Activity ofTetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine Derivatives as Epidermal GrowthFactor Receptor Inhibitors. Chemical Research in Chinese Universities, 2015,31(6): 936-941.9.Jianshu Hu, Wei Zhu, Hu Meng, Ying Liu, Xin Wangand Chun Hu*. Identification of 1, 4-Dihydrothieno[3′, 2′:5, 6]thiopyrano[4, 3-c]pyrazole Derivatives asHuman 5-Lipo-oxygenase Inhibitors. Chemical Biology and Drug Design, 2014,84(6): 642–647.10.Xin Wang, Rui Sun, Yushu Huang, Yisi Yan,Miaomiao Gao, Danni Wang, Diwa Koirala, Dawei Li, Chun Hu*. Development ofThieno[3',2':5,6]thiopyrano[4,3-c]pyrazole-3-carboxamide Derivatives as theEstrogen Receptor Ligands: Synthesis, Characterization and Biological Activity.Medicinal Chemistry, 2014, 10(8): 836-942.