导师姓名：蔡开勇
性别：男
人气指数：326

所属院校：重庆大学
所属院系：生物工程学院
职称：教授
导师类型：博导
招生专业：
研究领域： 1.层层自组装构建基因功能化生物活性材料2.组织诱导性钛/钛合金修复材料3.微纳米储池型药... [展开]


研究领域： 1.层层自组装构建基因功能化生物活性材料2.组织诱导性钛/钛合金修复材料3.微纳米储池型药物释放载体 [收起]




个人简述 :
男，教授，博导。2002年博士毕业于天津大学，2002-2005在德国Friedrich-Sciller-Jena?University做博士后研究，2005年加入重庆大学。系教育部长江学者特聘教授、第十二届中国青年科技奖获得者。任AIMS?Materials?Science、World?J?Stem?Cells、Advanced?Biomaterials等期刊编委，Advanced?Engineering?Materials?客座编辑。兼任Angew?Chem?Int?Ed,?Advanced?Materials,?J?Am?ChemSoc,?ACS?Nano,?Biomaterials等60余种国际期刊审稿人。主持或参与973、科技部支撑计划、国家自然科学基金重点/面上项目等20余项。近年来，在Angewandte?Chemie?Int?Ed,?Advanced?Materials,?ACS?Nano,?Biomaterials等期刊发表SCI论文70余篇，IF>5的20篇，其中IF>10的6篇。累计影响因子308分，SCI引用1000余次。国家发明专利授权8项，另有10余项申请中。

科研工作 :
代表性论文：1. Zhong Luo, KaiyongCai*, Yan Hu, Jinghua Li, Xingwei Ding, Beilu Zhang, Dawei Xu, WeihuYang, Peng Liu. Redox-responsive molecular nanoreservoirs for controlledintracellular anticancer drug delivery based on magnetic nanoparticles. Advanced Materials, 2012, 24,431-435. 2. Yan Hu, KaiyongCai*, Zhong Luo, Klaus D. Jandt. Layer-By-Layer Assembly of beta-estradiol loadedmesoporous silica nanoparticles on titanium substrates and its implication forbone homeostasis. Advanced Materials. 2010 22(37):4146-4150. 3. KaiyongCai*,Zhong Luo, Yan Hu, Xiuyong Chen, Li Yang, Linhong Deng. Magnetically triggeredreversible controlled drug delivery from microfabricated polymericmultireservoir devices. Advanced Materials. 2009 21(40):4045-4049. 4. Zhong Luo, KaiyongCai*, Yan Hu, Li Zhao, Peng Liu, Lin Duan, Weihu Yang. Mesoporoussilica nanoparticles end-capped with collagen: redox-responsive nanoreservoirsfor targeted drug delivery. Angew Chem Int Ed. 201150(3):640-643. 5. Kaiyong Cai*, Yan Hu, Zhong Luo, Ting Kong, Min Lai, XiaojingSui, Yuanliang Wang, Li Yang and Linhong Deng. Cell-specific gene transfectionfrom a gene-functionalized poly(D,L-lactic acid) substrate fabricated by thelayer-by-layer assembly technique. Angew. Chem. Int. Ed. 2008 47(39):7479-7481.6. Zhong Luo, Xingwei Ding, Yan Hu, Shaoquan Wu, YangXiang, Yongfei Zeng, Hong Yan, Hua-cheng Zhang, Liangliang Zhu, Junjie Liu,Jinghua Li, Kaiyong Cai*, andYanli Zhao*. Engineering a Hollow Nanocontainer Platform with MultifunctionalMolecular Machines for Tumor-Targeted Therapy in Vitro and in Vivo. ACSNano, 2013 in press.7. KaiyongCai*,Yanhua Hou, Yan Hu, Li Zhao, Zhong Luo, YisongShi, Min Lai, Weihu Yang, Peng Liu. Correlation of the cytotoxicity of TiO2nanoparticles with different particle sizes on a sub-200-nm scale.Small, 2011 7(21):3026-3031.8. Kaiyong Cai*, Jinghua Li, Zhong Luo, Yan Hu, Yanhua Hou,Xingwei Ding. beta-Cyclodextrin conjugated magnetic nanoparticles for diazepamremoval from blood. Chem Commun. 2011, 47 (27), 7719 – 7721.9. Yan Hu, KaiyongCai*, Zhong Luo, Yuan Zhang, Liqi Li, Min Lai, Yanhua Hou, Yuran Huang,Jinghua Li, Xingwei Ding, Bin Zhang, K L Paul Sung. Regulation of thedifferentiation of mesenchymal stem cells in vitro and osteogenesis in vivo bymicroenvironmental modification of titanium alloy surfaces. Biomaterials,2012 33(13):3515-3528.10. Yan Hu, KaiyongCai*,Rui Zhang, Zhong Luo, Li Yang, Klaus D. Jandt, Linhong Deng. Surface mediatedin situ differentiation of mesenchymal stem cells on gene-functionalizedtitanium films fabricated by layer-by-layer technique. Biomaterials. 200930(21):3626-3635.