导师姓名：金亮
性别：男
人气指数：1034

所属院校：中国药科大学
所属院系：生命科学与技术学院
职称：教授
导师类型：博导
招生专业：微生物与生化药学、生物学
研究领域： 1胰腺干/祖细胞在糖尿病治疗中的应用及开发；2人脂肪源干细胞在组织损伤中的应用与开发；3组... [展开]


研究领域： 1胰腺干/祖细胞在糖尿病治疗中的应用及开发；2人脂肪源干细胞在组织损伤中的应用与开发；3组织干细胞的正常发育、变异及肿瘤干细胞的形成机制；4用于糖尿病治疗的多肽类药物研究与开发； [收起]




通讯方式 :
办公电话：**
电子邮件：liangjin1975@cpu.edu.cn


个人简述 :
金亮， 博士，教授，江苏省特聘教授，博士生导师。2006年6月于中国药科大学获博士学位，同年8月留校任讲师；2010年5月晋升为副教授，同年7月赴美国国家医学中心（City of Hope）从事博士后研究，主要研究方向为胰腺干/祖细胞的分离、鉴定及定向分化。2014年5月返回中国药科大学。近5年主持及参与国家863计划项目，国家科技新药创制重大专项，国家自然科学基金项目等多项。发表SCI收录研究论文30余篇，授权专利5项。

科研工作 :
第一及通讯作者研究论文：1.Jin Liang, Wang Yu, Xiong Qiyan, Chen Qingmei, Li Jianping, Zhu Aihua, Cao Rongyue, Wu Jie, Liu Jingjing Long-lasting specific antibodies against p277 induced by mucosal administration of p277 repeat sequences carried by Hsp65 in the absence of adjuvants. Vaccine 2007 25: 2043-2050, (IF: 3.235).2.Liang Jin, Aihua Zhu, Yu Wang, Qingmei Chen, Qiyan Xiong, Taiming Li, Jie Wu, and Jingjing Liu*. A Th1 recognized peptide P277, when tandem repeated, induces a Th2 cytokine burst and toward effective vaccines against autoimmune diabetes in NOD mice. The journal of immunology 2008, 180 (1): 58 – 63, (IF: 4.856).3.Jin Liang, Zhu aihua, Wang Yu, Liu JingJing* Enhanced immunogenicity of peptide P277 by heat shock protein HSP65 vector carrying tandem repeats of P277 to prevent type 1 diabetes in NOD mice. Experimental and Clinical Endocrinology & Diabetes 2008, 116 (9):1-8, (IF: 1.685).4.Jin Liang, Zhu Aihua, Wang Yu, Lu Yong Liu Jingjing* HSP65 serves as an immunogenic carrier for a diabetogenic peptide P277 inducing anti-inflammatory immune response in NOD mice by nasal administration. Vaccine 2010, 28: 3312-33172, (IF: 3.235).5.Liang Jin, Tao Feng, Hung Ping Shih, Ricardo Zerda, Angela Luo, Jasper Hsu, Alborz Mahdavi, Maike Sander, David A. Tirrell, Arthur D. Riggs, and Hsun Teresa Ku*. Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel. PNAS 2013, 110 (10): 3907-3912, (IF: 9.661).6.Xianghui Fu, Liang Jin, Xichun Wang, Angela Luo, Junkai Hu, Xianwu Zheng, Walter M. Tsark, Arthur D. Riggs, H. Teresa Ku*. Wendong Huang MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation. PNAS 2013, 110 (44): 17892-17897, (Co-first, IF: 9.661).7.Liang Jin, Tao Feng, Ricardo Zerda, Ching-Cheng Chen, Arthur D. Riggs and Hsun Teresa Ku* In vitro multi-lineage differentiation and self-renewal of single pancreatic colony-forming cells from adult C57Bl/6 mice Stem Cells Dev 2014, 23 (8): 899-909, (IF: 3.562).8.Liang Jin,Tao Feng, Jing Chai, Nadiah Ghazalli, Dan Gao, Ricardo Zerda, Zhuo Li,Jasper Hsu, Alborz Mahdavi, David A. Tirrell, Arthur D. Riggs,and Hsun Teresa Ku*. Colony-forming progenitor cells in the postnatal mouse liver and pancreas give rise to morphologically distinct insulin-expressing colonies in 3D cultures. Rev Diabet stud 2014, 11(1):35-50, (IF: 2.94).9.Jin, Liang Gao, Dan Feng, Tao Tremblay, Jacob R. Ghazalli, Nadiah Luo, Angela Rawson, Jeffrey Quijano, Janine C. Chai, Jing Wedeken, Lena Hsu, Jasper LeBon, Jeanne Walker, Stephanie Shih, Hung-Ping Mahdavi, Alborz Tirrell, David A. Riggs, Arthur D. Ku, H. Teresa. Cells with surface expression of CD133^(high)CD71^(low) are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas. Stem Cell Research 2016, 16(1): 40-53, (IF: 3.494).