导师姓名：刘振
性别：女
人气指数：37

所属院校：天津科技大学
所属院系：生物工程学院
职称：助理研究员
导师类型：
招生专业：药理学
研究领域： [1]新型抗癌药物研究[2]药物药理作用研究
研究领域： [1]新型抗癌药物研究[2]药物药理作用研究 [收起]




通讯方式 :
办公电话：**
电子邮件：liuzhen5957@tust.edu.cn
通讯地址：天津经济技术开发区第十三大街29号天津科技大学生物工程学院


科研工作 :
发表科研论文11篇。1.Liu Z Zheng Q Chen WZ Wu M Pan GJ Yang K Li XZ Man SL Teng YO Yu P Gao WY. Chemosensitizing effect of Paris Saponin I on Camptothecin and 10-hydroxycamptothecin in lung cancer cells via p38 MAPK ERK and Akt signaling pathways. European Journal of Medicinal Chemistry 2017 125:760-769. 2.Liu Z Zheng Q Chen WZ Man SL Teng YO Meng X Zhang YM Yu P Gao WY. Paris saponin I inhibits proliferation and promotes apoptosis through down-regulating AKT activity in human non-small-cell lung cancer cells and inhibiting ERK expression in human small-cell lung cancer cells. RSC Advances 2016 6: 70816-70824. 3.Teng YO Wang LX Liu H Yuan Y Zhang Q Wu M Wang LY Wang HM Liu Z* Yu P*. 3'-Geranyl-mono-substituted chalcone Xanthoangelovl induces apoptosis in human leukemia K562 cells via activation of mitochondrial pathway. Chemico-Biological Interactions 2017 261:103-107.4.Liu Z Wang JY Gao WY Man SL Guo HM Zhang JZ Liu CX. Formulation and in vitro absorption analysis of Rhizoma paridis steroidal saponins. International Journal of Pharmaceutics 2013 441(1-2): 680-686. 5.Liu Z Li HF Fan YY Liu YX Man SL Yu P Gao WY. Combination treatment with Rhizoma Paridis and Rhizoma Curcuma longa extracts and 10-hydroxycamptothecin enhances the antitumor effect in H22 tumor model by increasing the plasma concentration. Biomedicine & Pharmacotherapy 2016 83: 627-634. 6.Liu Z Gao WY Man SL Zhang Y Li HF Wu SS Zhang JZ Liu CX. Synergistic effects of Rhizoma Paridis and Rhizoma Curcuma longa on different animal tumor models. Environmental Toxicology and Pharmacology 2014 38(1): 31-40. 7.Liu Z Gao WY Jing SS Zhang Y Man SL Wang Y Zhang JZ Liu CX. Correlation among cytotoxicity hemolytic activity and the composition of steroidal saponins from Paris L.. Journal of Ethnopharmacology 2013 149(2): 422-430. 8.Liu Z Wang JY Gao WY Man SL Wang Y Liu CX. Preparative separation and purification of steroidal saponins in Paris polyphylla var. yunnanensis by macroporous adsorption resins. Pharmaceutical Biology 2013 51(7): 899-905. 9.Liu Z Zhang JZ Gao WY Liu CX. Antinociceptive activity and Chemical composition of Wei-Chang-An-Wan extracts. Pharmaceutical Biology 2013 51: 790-797. (IF: 1.546，4区)10.Liu Z Li N Gao WY Man SL Yin SS Liu CX. Comparative study on hemostatic cytotoxic and hemolytic activities of different species of Paris L.. Journal of Ethnopharmacology 2012 142(3): 789-794. 11.Liu Z Gao WY Man SL Wang JY Li N Yin SS Wu SS. Liu CX. Pharmacological evaluation of sedative-hypnotic activity and gastro-intestinal toxicity of Rhizoma Paridis saponins. Journal of Ethnopharmacology 2012 144(1): 67-72.