导师姓名：张兰威
性别：男
人气指数：721

所属院校：东北农业大学
所属院系：乳品科学教育部重点实验室
职称：教授
导师类型：硕导
招生专业：食品科学


通讯方式 :
办公电话：**
电子邮件：zhanglw@hit.edu.cn


科研工作 :
l国家自然基金:保加利亚乳杆菌蛋白酶的凝乳特性及其相关基因发掘研究,2013.1-2016.122国家自然基金:黏玉米来源的TGase定向改造及在巴氏毕赤酵母中高效表达2010.1-2012.123国家自然基金：亚油酸异构酶定向进化及在嗜热链球菌中高效表达，2009.1-2011.124国家科技部十二五科技支撑：乳制品加工厂废水的回收利用（2013BAD18B05-05），2013.1-2016.125十二五农村领域国家科技计划（科技部）：利用酪蛋白胶束-乳铁蛋白动态包裹-释放机制开发活性乳铁蛋白分离的集成膜过滤技术2013BAD18B06-03，2013**6国家科技部863高科技项目：发酵肉制品与玉米及膳食纤维工程化加工新技术研究，2011.1-2016.127国家“十一五”支撑：东北农区奶业集约化生产技术集成及产业化示范——新型乳制品开发与示范，2006.1-2010.128国家教育部：副干酪乳杆菌J23分泌ClassⅡa抗菌肽AMPY化学结构表征及其抑菌机制的研究，2012.1-2015.129国家863计划：益生菌定向选育及其高活性制品开发关键技术，2007.1-2010.1210黑龙江省教育厅：中美食品科学与工程研究生教育模式比较研究，2012.1-2013.12”。近五年代表性著作、论文：2015年发表的主要论文（通信作者）lShuangZhang,LanweiZhang,YuehuaJiao,etal,Lactobacillusdelbrueckiisubsp.bulgaricusProteinase:PurificationbyIon-exchangeandHydrophobicInteractionChromatography,LJFP#921199,VOL00,ISS00.lShuangZhang,LanweiZhang,LiliZhang,etal,purification,andcharacterizationofproteinasefrom3Lactobacillusdelbrueckiisubsp.bulgaricus,RSCAdv.,2015,5,93733-93738lPei-JunTian,Bao-LongLi,Yu-JuanShan,Jin-NaZhang,Jing-YuChen,MinYuandLan-WeiZhang*,ExtractionofPeptidoglycanfromL.paracaseisubp.ParacaseiX12andItsPreliminaryMechanismsofInducingImmunogenicCellDeathinHT-29Cells,Int.J.Mol.Sci.2015,16,20033-20049lHONGBOLI,YANHUACUI,LANWEIZHANG*，etal.,ProductionofatransglutaminasefromZeamaysinEscherichiacolianditsimpactonyoghurtproperties,68(1),2015InternationalJournalofDairyTechnologylWenliLiu,LanweiZhang,JohnShi,etal.,AssessmentofthesafetyandapplicationsofbacteriocinogenicEnterococcusfaeciumY31asanadjunctcultureinNorth-easternChinesetraditionalfermentationpaocai,FoodControl,50(2015)**年发表主要论文（通信作者）：lHongboLi,YanhuaCui,LanweiZhang,etal.HeterologousexpressionandpurificationofZeamaystransglutaminaseinPichiapastoris[J].FoodScienceandBiotechnology.lPiminGong,LanweiZhang*,XueHan,NditangeShigwedha,InjuryMechanismsofLacticAcidBacteriaStarterCulturesDuringSprayDrying:AReviewpages,DryingTechnology,32(7),2014:793-800lShumeiWang,LanweiZhang,RongboFan,etal,InductionofHT-29cellsapoptosisbylactobacilliisolatedfromfermentedproducts,ResearchinMicrobiology,2014,165(3):202–214.lFupingXu,YangCao,ZheWang,LanweiZhang*,etal.Theoleochemicalpropertiesofostrichabdominalfatincomparisonwithchickenandduckfats.[J]InternationalJournalofFoodScienceandNutrition.2014.190（1）17:lXueHan,LanweiZhang*,PengYu,etal,PotentialofLABstartercultureisolatedfromChinesetraditionalfermentedfoodsforyoghurtproductionInternationalDairyJournal，34（2）(2014)：247-251lHongboLi,LanweiZhang,YanhuaCui,etal,CharacterizationofrecombinantZeamaystransglutaminaseexpressedinPichiapastorisanditsimpactonfullandnon-fatyoghurts[J].JournaloftheScienceofFoodandAgriculture,2014,94(6):1225-1230.2013年发表主要论文（通信作者）lChaohuiXue,LanweiZhang,HongboLi,etal.FunctionalityoftheS-layerproteinsfromLactobacillusinthecompetitiveagainstenteropathogensinfection,EuropeanFoodResearchandTechnology,(2013)236:249-255.lHongboLi,LanweiZhang,YanhuaCui,XueLuo,etal.ExpressionofsolublerecombinanttransglutaminasefromZeamaysinPichiapastoris,WorldJournalofMicrobiologyandBiotechnology,(2013),29:939-947.lHuaxiYi,XueHan,YanyanYang,etal,EffectofExogenousFactorsonBacteriocinProductionfromLactobacillusparacaseiJ23byUsingaRestingCellSystem,InternationalJournalofMolecularSciences,2013,14(12):24355-24365.lFupingXu,LanweiZhang,YangCao,etal.ChemicalandPhysicalCharacterizationofDonkeyAbdominalFatinComparisonwithCow,PigandSheepFats,JournaloftheAmericanOilChemists'Society,(2013)90:1371-1376.lJingyanLi,LanweiZhang,XueHan,HuaxiYi,etal.Effectofincubationconditionsandpossibleintestinalnutrientsoncis-9,trans-11conjugatedlinoleicacidproductionbyLactobacillusacidophilusF0221,InternationalDairyJournal,(2013)29:93-98.lMengLiu,MingDu,YingchunZhang,WeiliXu,CongWang,KejianWang,LanweiZhang.PurificationandIdentificationofanACEInhibitoryPeptidefromWalnutProtein,JournalofAgriculturalandFoodChemistry,(2013),61:4097-4100lXueLuo,LanweiZhang,HongboLi,ShuangZhang,YuehuaJiao,ShumeiWang,ChaohuiXue,RongboFan.ComparisonofenzymaticactivityoftwolinoleicacidisomerasesexpressedinE.coli,MolecularBiologyReports,(2013)40:5913-5919.lYanfengTuo,WeiqinZhang,LanweiZhang,LianzhongAi,YingchunZhang,XueHan,HuaxiYi.StudyofprobioticpotentialoffourwildLactobacillusrhamnosusstrains,Anaerobe,(2013)21:22-27.lYanhuaLi,LanweiZhang,WeijunWang.Heat-inducedChangesinVolatilesofMilkandEffectsofThermalProcessingonMicrobialMetabolismofYogurt,JournalofFoodBiochemistry,(2013)37(4):409-417lYanhuaLi,LanweiZhang,WeijunWang,XueHan.Differencesinparticlecharacteristicsandoxidizedflavorasaffectedbyheat-relatedprocessesofmilkpowder,JournalofDairyScience,(2013)96(8):4784-4793.lYujuanShan,LanweiZhang,YongpingBao,BaolongLi,CanxiaHe,MingmingGao,XueFeng,WeiliXu,XiaohongZhang,ShuranWang.Epithelial-mesenchymaltransition,anoveltargetofsulforaphaneviaCOX-2/MMP2,9/Snail,ZEB1andmiR-200c/ZEB1pathwaysinhumanbladdercancercells,JournalofNutritionalBiochemistry,(2013)24:1062-1069.2012年发表主要文章（通信作者）lChunfengGuo,LanweiZhang,XueHan,etal.Screeningforcholesterol-loweringprobioticbasedondeoxycholicacidremovalpathwayandstudyingitsfunctionalmechanismsinvitro.Anaerobe(2012)18:516-522.lChunliMa,LanweiZhang,DexingMa,etal.TechnologicalcharacterisationofLactobacilliisolatedfromChineseartisanalfermentedmilks.InternationalJournalofDairyTechnology2012,65(1):132-139.lLiliZhang,LanweiZhang,HuaxiYi,etal.EnzymaticcharacterizationoftransglutaminasefromStreptomycesmobaraensisDSM40587inhighsaltandeffectofenzymaticcross-linkingofyakmilkproteinsonfunctionalpropertiesofstirredyogurt.JournalofDairyScience.2012,95(7):3559-3568.lLiliZhang,LanweiZhang,HuaxiYi,etal.EnhancementoftransglutaminaseproductioninStreptomycesmobaraensisDSM40587bynon-nutritionalstressconditions:Effectsofheatshock,alcohols,andsalttreatments.KoreanJournalofChemicalEngineering.2012,29(7):913-917.lLiliZhang,LanweiZhang,XueHan,etal.EnhancementoftransglutaminaseproductioninStreptomycesmobaraensisasachievedbytreatmentwithexcessiveMgCl2.AppliedMicrobiologyandBiotechnology.(2012)93:2335-2343.IF=3.689(2013)lWeijunWang,LanweiZhang,YanhuaLi.ProductionofVolatileCompoundsinReconstitutedMilkReduced-FatCheeseandthePhysicochemicalPropertiesasAffectedbyExopolysaccharide-ProducingStrain.Molecules.2012,17(12):14393-14408.lWeijunWang,LanweiZhang,YanhuaLi,ZhenFeng.Heat-InducedProteinAggregatesandDifferenceintheTexturalPropertiesofWholeMilkGel.JournalofFoodQuality.2012,35(4):247-254.IF=0.758(2013)lXiaohongKang,NanLing,GuoqingSun,QiZhou,LanweiZhang,QinghaiSheng.CompleteGenomeSequenceofStreptococcusthermophilusStrainMN-ZLW-002.JournalofBacteriology.2012,194(16):4428-4429.lYanhuaCui,ChaoZhang,YunfengWang,JohnShi,LanweiZhang,ZhongqingDing,XiaojunQu,HongyuCui.ClassIIaBacteriocins:DiversityandNewDevelopments.InternationalJournalofMolecularSciences.2012,13(12):16668-16707.lYanhuaCui,WeiLiu,XiaojunQu,ZhangtingChen,XuZhang,TongLiu,LanweiZhang.AtwocomponentsystemisinvolvedinacidadaptationofLactobacillusdelbrueckiisubsp.Bulgaricus.MicrobiologicalResearch.(2012)167:253-261.lYanhuaLi,LanweiZhang,WeijunWang.FormationofAldehydeandKetoneCompoundsduringProductionandStorageofMilkPowder.Molecules.2012,17(8):9900-9911.lYingchunChang,LanweiZhang,WeiMa,etal.ScreeningofprobioticlactobacilliforinhibitonofShigellasonneiandthemacromoleculesinvolvedininhibition.Anaerobe,2012,18(5):498-503.、论著（1）主编全国统编教材4部：《发酵食品原理与技术》主编（十二五规划教材，科学出版社2013年）、《乳与乳制品工艺学》（主编，中国农业出版社2006），《发酵食品工艺学》主编（十一五规划教材，中国轻工出版社2011年），《畜产食品工艺学》（第二编者十五规划教材教材，中国农业出版社，2002.7）；主编国家级出版社专著1部（中国农业出版社，2002.2）；主编省级公开出版著作、教材3部（黑龙江科技社1996；哈尔滨工程大学出版社，1997；2003.2）；副主编百科书1部《中国乳业大百科》，参编《中国保健食品进展》（人民卫生出版社，2001）；